A disabled man is haunted by the torture he suffered as a child when his terminally ill half-sister returns to their small Upstate New York town seeking answers to why their mother abandoned her 40 years before, which sets them both on a tragic and horrific journey.
An unhappy lion mascot, a straight talking chick fed up with sexual double standards, a hypochondriac 18 year old gay guy who just got into med school: all these colorful characters collide in fragments filled with sex talk and humor, with the ever inspiring New Orleans as a backdrop.